CAS #: 863288-34-0
Research Use Only
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CJC-1295 No DAC Overview
CJC-1295 No DAC is a modified GHRH(1-29) analog incorporating four amino acid substitutions at positions 2, 8, 15, and 27 designed to confer resistance to dipeptidyl peptidase-4 (DPP-4)
degradation while preserving receptor binding affinity. Unlike the DAC-modified version with extended half-life, this variant maintains a shorter duration of action (approximately 30 minutes), enabling amplification of physiologic GH pulse patterns rather than sustained elevation. Research models examine its effects on pituitary GHRH receptor activation, growth hormone secretagogue activity, IGF-1 pathway stimulation, circadian GH rhythm modulation, and metabolic signaling in laboratory settings.
CJC-1295 no DAC Structure
CAS #: 863288-34-0
Molecular Formula: C₁₆₅H₂₆₉N₄₇O₄₆
Molecular Weight: 3647.28 g/mol
PubChem ID: 91976529
Storage (unopened): Cool, dry, protected from light. Follow approved internal laboratory SOPs.












