CJC-1295 No DAC Overview
CJC-1295 No DAC is a modified GHRH(1-29) analog incorporating four amino acid substitutions at positions 2, 8, 15, and 27 designed to confer resistance to dipeptidyl peptidase-4 (DPP-4)
degradation while preserving receptor binding affinity. Unlike the DAC-modified version with extended half-life, this variant maintains a shorter duration of action (approximately 30 minutes), enabling amplification of physiologic GH pulse patterns rather than sustained elevation. Research models examine its effects on pituitary GHRH receptor activation, growth hormone secretagogue activity, IGF-1 pathway stimulation, circadian GH rhythm modulation, and metabolic signaling in laboratory settings.

Ipamorelin Overview
Ipamorelin is a synthetic pentapeptide and selective secretagogue-type agonist. It is studied in preclinical and experimental research for its selective pituitary signaling activity with minimal off-target pathway interference. This selectivity makes it an important tool for investigating endocrine signaling, somatotroph axis modulation, and related molecular pathways.

Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Structure
CJC-1295 (no DAC) / Modified GRF(1-29)
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.92 g/mol
CAS Number: 863288-34-0
Sequence / Structure: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-
Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Classification: 29-residue modified GHRH analog
Ipamorelin
Molecular Formula: C38H49N9O5
Molecular Weight: 711.85 g/mol
CAS Number: 170851-70-4
Sequence / Structure: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Classification: Synthetic pentapeptide
Storage (unopened): Cool, dry, protected from light. Follow approved internal laboratory SOPs.